Phytochemical Screening and Evaluation of the Antimicrobial Activity of Hydroethanolic Extract from the Leaves of Anogeissus leiocarpa (DC.) Guill. & Perr. (Combretaceae)

Sarr A — 2025-10-10

Background: For centuries, traditional medicine has been a source of reliable, acceptable and affordable healthcare for African populations. Despite the development of modern medicine in subsequent years, this tradition has spread widely from one country to another and from generation to generation. To date, 80% of the continent's population has used traditional medicine to meet their essential health needs.

Aim: The aim of this study was to determine the phytochemical composition and evaluate the antimicrobial activity of the hydroethanolic extract of the leaves of Anogeissus leiocarpa (DC.) Guill. & Perr. (Combretaceae).

Results: Extraction of 30 g of Anogeissus leiocarpa leaf powder obtained yields of 20.66%. The phytochemical screening showed the presence of alkaloids, flavonoids, condensed tannins, hydrolysable tannins, sterols and saponosids. Leaf extracts from Anogeissus leiocarpa contained 174.79±3,31 mg EAG/g polyphenols and had a flavonoid content of 323.87±0.40 mg ER/g. Antimicrobial screening carried out on microbial strains (Staphylococcus aureus, Escherichia coli and Candida albicans) showed inhibition diameters of 25.33±1.73 mm, 24.66±0.57 mm and 32.33±0.57 mm, respectively. The MICs obtained were 1.25 µg/µl, 2.5 µg/µl and 1.25 µg/µl for S. aureus, E. coli and C. albicans, respectively. And then, the MBCs obtained were 2.5 µg/µl, 5 µg/µl and 1.25 µg/µl for S. aureus, E. coli and C. albicans, respectively.

Conclusion: In view of these results, this plant could offer hope in the treatment of microbial diseases, which pose a real threat to public health.

Ethnopharmacological Study of Plants Used against Malaria by Traditional Healers in the District of Dikodougou, North Côte d'Ivoire

Koffi Akissi Jeanne — 2025-10-11

Traditional medicine (TM) has been a cornerstone of healthcare in many cultures, particularly in Africa. TM has played an integral role in managing diseases such as malaria. In Côte d'Ivoire, limited access to medical facilities brought indigenous communities to use on herbal medicine to prevent and manage malaria. As part of the effort to discover new bioactive molecules from plants, a study was conducted on medicinal plants used to treat malaria in the Dikodougou district. The survey was based on questionnaires and interviews with fifteen traditional practitioners who had knowledge of antimalarial medicinal plants. A total of 24 species of medicinal plants were identified. The most representatives plants families were Fabaceae, Asteraceae, Rubiaceae, Meliaceae, and Phyllanthaceae. Cassia sieberiana DC (Fabaceae) was much more species cited, at 35.29%. Pericopsis laxiflora (Benth. ex Baker) Meeuwen (Fabaceae) followed with 23.53%, followed by Sarcocephalus latifolius Sin (Rubiaceae), Tamarindus indica L (Fabaceae), and Flueggea virosa (Roxb. ex Willd.) Royle (Phyllanthaceae). The parts of plants frequently used by traditional healers were leaves (51.11%), followed by roots (28.89%) and seeds (11.11%). The most preparation methods used by traditional healers was decoction (50%) and maceration (40%). Evaluating the antimalarial properties of the most commonly cited species would validate the knowledge and practices of traditional practitioners in the Dikodougou district.

Journal of Advances in Medical and Pharmaceutical Sciences

Phytochemical Screening and Evaluation of the Antimicrobial Activity of Hydroethanolic Extract from the Leaves of Anogeissus leiocarpa (DC.) Guill. & Perr. (Combretaceae)

Ethnopharmacological Study of Plants Used against Malaria by Traditional Healers in the District of Dikodougou, North Côte d'Ivoire