Journal of Advances in Medical and Pharmaceutical Sciences https://journaljamps.com/index.php/JAMPS <p style="text-align: justify;"><strong>Journal of Advances in Medical and Pharmaceutical Sciences (ISSN:&nbsp;2394-1111)</strong> aims to publish high quality papers (<a href="/index.php/JAMPS/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;Medical and Pharmaceutical Sciences. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer reviewed, open access INTERNATIONAL journal.&nbsp;</p> SCIENCEDOMAIN international en-US Journal of Advances in Medical and Pharmaceutical Sciences 2394-1111 The Possible Protective Effect of Metformin in COVID-19 Infection https://journaljamps.com/index.php/JAMPS/article/view/30185 <p>Coronavirus 2019 (COVID-19) infections with more than 30 million confirmed cases are increasing rapidly, requiring urgent and safe treatment. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), a virus responsible for the infection of COVID-19. Metformin (M) is a biguanide drug used as a first choice for the management of hyperglycemia in type 2 diabetes mellitus (T2DM). Furthermore, it is safe and currently available. It is speculated that metformin can be used for T2DM patients with COVID-19, because in addition to its hypoglycemic effect, this biguanide also shows many beneficial effects, including anti-inflammatory effects and cardiopulmonary protection especially by angiotensin converting enzyme 2 (ACE2) targeting. Therefore, the reasons for the use of metformin in COVID-19 patients were discussed in this study. Metformin has a promising role in treatment of COVID-19 in T2DM and obese women patients.</p> Waleed K. Abdulsahib ##submission.copyrightStatement## 2020-10-20 2020-10-20 1 5 10.9734/jamps/2020/v22i830185