Journal of Advances in Medical and Pharmaceutical Sciences 2023-02-03T12:34:12+00:00 Journal of Advances in Medical and Pharmaceutical Sciences Open Journal Systems <p style="text-align: justify;"><strong>Journal of Advances in Medical and Pharmaceutical Sciences (ISSN:&nbsp;2394-1111)</strong>&nbsp;aims to publish high quality papers (<a href="/index.php/JAMPS/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;Medical and Pharmaceutical Sciences.&nbsp;By not excluding papers based on novelty, this journal facilitates the research and wishes to publish papers as long as they are technically correct and scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled, OPEN peer-reviewed, open-access INTERNATIONAL journal.</p> Characteristics of Male Perpetrators of Intimate Partner Violence in South-South Nigeria 2023-01-09T08:02:59+00:00 K. Itimi S. S. Uriah A. Dan-Jumbo P. O. Dienye <p><strong>Aims:</strong> This study was done to identify personal characteristics of men that may be associated with partner abuse in order to provide a basis for offering counseling services, to prevent, as well as appropriately manage cases of existing abuse.</p> <p><strong>Study Design:</strong> Cross sectional survey.</p> <p><strong>Place and Duration of Study:</strong> The study was done at the General Outpatients Clinic of University of Port Harcourt Teaching Hospital, Port Harcourt, Rivers State, Nigeria; between August and November 2007.</p> <p><strong>Methodology:</strong> The examiner administered pre-tested questionnaire on adult females attending the clinic within the duration of the study. Every second patient seen by the investigator on the waiting line of a regular medical consultation visit that consented to the study was recruited until the desired sample size was got. Socio-demographic as well as drug use information of adult subjects’ partners aged between 18 to 59 years was obtained.</p> <p><strong>Results:</strong> Of the 384 females investigated, age 21 – 67 years with a mean age of 31.31±8.61 years: physical abuse 41.9%, verbal/emotional abuse 49.0%, and a combined (physical/verbal) abuse 29.9%. Partners’ education had statistically significant relationship with physical abuse, P=0.018; partners’ tobacco uses with verbal abuse (P=0.000), and between combined abuse and use of tobacco or cannabis, P=0.003 and 0.048 respectively.</p> <p>Linear multiple regression model of physical abuse parameters: throw something at, being pushed, slapped, kicked, hit at, beaten-up, threatened or weapon used, and forced sex; P-value was 0.000, with sum of squares 60.263 and degree of freedom 9. Whereas for verbal abuse: cajoled, derogatory statements made at, name calling, and shout at, as abuse parameters; P-value was 0.000, sum of squares 72.763 and degree of freedom, 4. Both of these were statistically significant.</p> <p><strong>Conclusion:</strong> This study demonstrates a higher perpetration of verbal/emotional violence than that of physical violence (or both) by males on their partners with lack of formal education, with tobacco and/or cannabis use, as aggravating factors.</p> 2022-12-29T00:00:00+00:00 ##submission.copyrightStatement## Clinical Correlates of Type 2 Diabetic Patients with Erectile Dysfunction Attending the Family Medicine Clinic in a Southern State of Nigeria 2023-01-18T12:15:48+00:00 B. E. Ikpae S. S. Uriah A. Dan-Jumbo P. O. Dienye <p><strong>Aims:</strong> This study aimed to provide evidence on the clinical correlates of type 2 diabetic patients with erectile dysfunction leading to improved quality of life.&nbsp;</p> <p><strong>Study Design</strong><strong>:</strong> Cross-sectional study.</p> <p><strong>Place and Duration of Study</strong><strong>:</strong> Family Medicine Clinic of Braithwaite Memorial Specialist Hospital (BMSH) [now Rivers University Teaching Hospital] Port Harcourt. The data was collected from January 2012 to April 2012.</p> <p><strong>Methodology</strong><strong>:</strong> This hospital-based study was conducted on 324 male type 2 diabetic patients using systematic random sampling. The data were collected with a structured questionnaire; and the level of erectile dysfunction was measured using the international index of erectile function. Data was entered and analyzed using SPSS version 16. Logistic regression was employed to test associations between independent and outcome variables.</p> <p><strong>Results: </strong>Three hundred and twenty-four patients enrolled for the study. Only 31 participants (9.5%) had normal erectile function while 273 (90.5%) had varying degree of erectile dysfunction. Majority of the participants 205(63.2%) had diabetes above 20 years, more than half (64.9%) had poor glucose control, 169(52.1%) were overweight, while 284(87.6%) had normal cholesterol level and 186(57.4%) with elevated diastolic blood pressure. Duration of diabetes and diastolic hypertension were the only factors associated with erectile dysfunction p&lt;0.0001 and p&lt;0.004 respectively.</p> <p><strong>Conclusion: </strong>This study confirmed a high prevalence of ED in type 2 diabetic male patients especially among those with elevated blood pressure and those living with diabetes mellitus for many years.</p> 2022-12-29T00:00:00+00:00 ##submission.copyrightStatement## Analysis of Patients with Emergency Thoracic Trauma 2023-01-19T12:16:01+00:00 Bayrakçi Onur <p><strong>Background: </strong>Trauma is an important health problem because it causes high morbidity and mortality. Thoracic trauma is generally categorized as blunt and penetrating trauma. Thoracic traumas are life-threatening and require rapid intervention. Successful treatment is achieved with multidisciplinary management and rapid diagnosis.</p> <p><strong>Aims:</strong> It was aimed to investigate clinical outcomes of emergency thoracic trauma in the study.</p> <p><strong>Study Design: </strong>Trauma patients older than 18 years old hospitalized to the thoracic surgery clinic from the emergency department were included and, patients were excluded without thoracic trauma, not hospitalized, and younger than 18 years of ages in the study.</p> <p><strong>Place and Duration of Study: </strong>Ersin Arslan Training and Research Hospital wards of thoracic surgery from January 1, 2021 to December 31, 2021.</p> <p><strong>Methodology:</strong> A total of 114 patients were analyzed. The data of the patients were analyzed ages, gender, comorbidities, smoking, use of alcohol and other substances, types of trauma, localization and variety of injuries, pathological findings on thoracic and extrathoracic organs, methods of medical and surgical treatments, lenght of stays in Intensive-care Unit and hospital, recovery and mortality. Statistical analysis of the study was done using the Chi-square test.</p> <p><strong>Results:</strong> Patients were 87.7% males and 12.3% females. The mean age was 40.3+/-10.8. Comorbidities were 20.2. The rates of use of substances were cigarettes 75.4%, alcohol 14.8% and other substances 15.7%. The rates of types of traumas were 14% Motor Vehicle Collisions, 6.1% Vehicles Striking Pedestrians, 3.5% Acts of Violence, 29.8% stabbing, 13.2% gunshot wounds, 33.4% falls. . Findings of thoracic injuries were 75.4% hemothorax, 72.8% pneumothorax, 61.4% contusion of the lungs, 49.1% fractures of the ribs, 18.4% subcutaneous emphysema, 9.6% cardiac injury, 5.2% diaphragmatic, 1.7% tracheobronchial and 0.8% esophageal injury. Surgically, which were 32.4% tube thoracostomy, 15.7% primary repair, and 10.5% thoracotomy among all traumas. The maximum length of stay in the Intensive-care Unit were for acts of violence and gunshot wounds and the maximum length of stay in the hospital were in acts of violence and falls from height.</p> <p><strong>Conclusions: </strong>Thoracic traumas were more often in males. Penetrating injuries were more common in adults younger than 40 years and blunt traumas in adults older than 40 years. The majority of patients were without comorbidity. Surgically, these were done 100% parenchyma of the lung repair, 75% intercostal ligation, 41.6% thoracic wall reconstruction, 33.3% mediastinal surgery and 25% diaphragm repair in patients with thoracotomy. Rates of mortality were 13.3% in gunshot wounds and 2.9% in stabbing. Mortality rate was 2.6% in all thoracic traumas in the study.</p> 2022-12-29T00:00:00+00:00 ##submission.copyrightStatement## Practices and Barriers towards Pharmacovigilance and Adverse Drug Reporting among Intern Pharmacists in Nigeria 2023-02-03T12:34:12+00:00 Shadrach Chinecherem Eze Evaristus Chinonso Odoh Kingsley Chinemerem Eze Wisdom Enyinnaya Arugo Gerald Obinna Ozota Ugomma Loveth Anyaji Collins Chukwuemeka Magbo Chidimma Elizabeth Mbakamma Victor Chikaodiri Amaechi Chimaobi Jude Nwiyi Kennedy Onyedikachi Ijegalu Goodness Chizorom Nwokebu <p><strong>Background: </strong>The practice of Pharmacovigilance (PV) and Adverse Drug Reaction (ADR) reporting is very necessary to ensure adequate safety of all drugs in use and is an integral component of post marketing surveillance. Pharmacist, including interns are at a central position in carrying out this important function.</p> <p><strong>Objectives: </strong>This study sought to assess the practice of&nbsp; pharmacovigilance and adverse drug reaction reporting and the perceived barriers towards its implementation among pharmacist interns in Nigeria.</p> <p><strong>Methods: </strong>This was a cross-sectional study among pharmacist interns in Nigeria. The 18-item semi-structured questionnaires were administered online using simple random sampling with the snowballing technique to recruit the participants and the results were analyzed with IBM SPSS version 25. Descriptive statistics were used to summarize the data. The chi-square test was used to evaluate associations.</p> <p><strong>Results: </strong>A total of 450 pharmacist interns participated in this study. The practice of PV and ADR reporting is poor among the respondents, less than 40% of the participants have ever reported ADR before, while only 29.1% have reported ADR since starting their internship program. Only 35.8% said “yes” to documenting ADR. Verbal information (61.1%) is the most widely used method of reporting ADR. Lack of cohesion among healthcare professionals, unavailability of feedback from relevant authorities, and fear of being wrong are the most reported barriers towards PV and ADR reporting among the participants. This is a correlation between the number of months spent in internship program and the practice of PV by the participants.&nbsp; ‘Fear of being wrong’ is an essential barrier to PV and ADR reporting among participants in tertiary hospitals (86.0%).</p> <p><strong>Conclusion: </strong>The practice of pharmacovigilance is poor among the participants. Many barriers also affect ADR reporting among the interns. Measures should be taken to encourage ADR reporting and the reported barriers should be reviewed to improve pharmacovigilance activities.</p> 2022-12-31T00:00:00+00:00 ##submission.copyrightStatement##