Analysis of the Mechanism of Ophiopogon japonicus in Treating Pneumonia Based on Network Pharmacology

Zheng Wang

School of Life Science and Engineering, Southwest University of Science and Technology, China.

Peinan Wan

School of Life Science and Engineering, Southwest University of Science and Technology, China.

Mingxiu Li

School of Life Science and Engineering, Southwest University of Science and Technology, China.

Yi Huang *

School of Life Science and Engineering, Southwest University of Science and Technology, China.

*Author to whom correspondence should be addressed.


Abstract

This study explores the mechanism of Ophiopogon japonicus in treating pneumonia through network pharmacology, establishes a physiological and pharmacological relationship between the two based on targets, and emphasizes the interaction between signaling pathways and targets. By utilizing Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis, specific biological processes and signaling pathways are utilized to enhance the understanding of the medicinal properties of traditional Chinese medicine through the use of bioinformatics and biomedical tools. This method aims to identify the key targets and signaling pathways of Ophiopogon japonicus affecting pneumonia status, providing insights into its anti-inflammatory effect in the lungs. The active application of network pharmacology methods in the field of pneumonia is a new trend in the modernization of traditional Chinese medicine.

Keywords: Network pharmacology, Ophiopogon japonicus, pneumonia, signal pathway


How to Cite

Wang, Zheng, Peinan Wan, Mingxiu Li, and Yi Huang. 2024. “Analysis of the Mechanism of Ophiopogon Japonicus in Treating Pneumonia Based on Network Pharmacology”. Journal of Advances in Medical and Pharmaceutical Sciences 26 (6):64-74. https://doi.org/10.9734/jamps/2024/v26i6696.

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