Human Amniotic Membrane Graft Plug for Sclerotomy Closure of 23-Gauge Pars Plana Vitrectomy in Eyes with Silicone Oil Tamponade

Hussain Ahmad Khaqan

Department of Ophthalmology, Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

Laraib Hassan *

Department of Ophthalmology, Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

Hafiz Ateeq ur Rehman

Department of Ophthalmology, Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

Aamna Jabran

Department of Ophthalmology, Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

Nabeel Akram

Department of Ophthalmology, Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

Ahmad Fauzan

Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

*Author to whom correspondence should be addressed.


Abstract

The aim of this single-center, comparative, interventional case study is to elaborate a method to plug the 23-gauge pars plana vitrectomy sclerotomy using a human amniotic membrane in the eyes having internal tamponade of silicone oil. This study was conducted on 75 eyes of 75 patients who underwent 23-gauge pars plana vitrectomy with tamponade of silicone oil. Patients were divided into three groups based on sclerotomy closure. Group A consisted of 25 eyes in which the sclerotomy was closed with a human amniotic membrane, Group B consisted of 25 eyes in which the sclerotomy was closed with sutures, and Group C consisted of 25 eyes in which neither sutures nor human amniotic membrane were used. Patients were monitored for a total of six months. Hypotony and subconjunctival silicone oil were not seen in Group A. 12% of those in Group B had subconjunctival silicone oil leaks, but none had hypotonia. On the first postoperative day in Group C, 28% displayed subconjunctival silicone oil, and 16% displayed hypotonia. Further manipulation was required for these four hypotonus eyes; two required the use of sutures, and the other two required the use of a human amniotic membrane. We came to the conclusion that silicone oil tamponade with a human amniotic membrane plug appears to be a promising method for closing the vitrectomy sclerotomy in the eyes.

Keywords: Human amniotic membrane, pars plana vitrectomy, sclerotomy, silicone oil tamponade


How to Cite

Khaqan, H. A., Hassan , L., Rehman , H. A. ur, Jabran , A., Akram , N., & Fauzan , A. (2024). Human Amniotic Membrane Graft Plug for Sclerotomy Closure of 23-Gauge Pars Plana Vitrectomy in Eyes with Silicone Oil Tamponade. Journal of Advances in Medical and Pharmaceutical Sciences, 26(5), 42–48. https://doi.org/10.9734/jamps/2024/v26i5685

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