Human Amniotic Membrane Graft Plug for Sclerotomy Closure of 23-Gauge Pars Plana Vitrectomy in Eyes with Silicone Oil Tamponade

Hussain Ahmad Khaqan

Department of Ophthalmology, Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

Laraib Hassan *

Department of Ophthalmology, Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

Hafiz Ateeq ur Rehman

Department of Ophthalmology, Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

Aamna Jabran

Department of Ophthalmology, Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

Nabeel Akram

Department of Ophthalmology, Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

Ahmad Fauzan

Post Graduate Medical Institute, Ameer-ud-Din Medical College, Lahore General Hospital, Lahore, Pakistan.

*Author to whom correspondence should be addressed.


Abstract

The aim of this single-center, comparative, interventional case study is to elaborate a method to plug the 23-gauge pars plana vitrectomy sclerotomy using a human amniotic membrane in the eyes having internal tamponade of silicone oil. This study was conducted on 75 eyes of 75 patients who underwent 23-gauge pars plana vitrectomy with tamponade of silicone oil. Patients were divided into three groups based on sclerotomy closure. Group A consisted of 25 eyes in which the sclerotomy was closed with a human amniotic membrane, Group B consisted of 25 eyes in which the sclerotomy was closed with sutures, and Group C consisted of 25 eyes in which neither sutures nor human amniotic membrane were used. Patients were monitored for a total of six months. Hypotony and subconjunctival silicone oil were not seen in Group A. 12% of those in Group B had subconjunctival silicone oil leaks, but none had hypotonia. On the first postoperative day in Group C, 28% displayed subconjunctival silicone oil, and 16% displayed hypotonia. Further manipulation was required for these four hypotonus eyes; two required the use of sutures, and the other two required the use of a human amniotic membrane. We came to the conclusion that silicone oil tamponade with a human amniotic membrane plug appears to be a promising method for closing the vitrectomy sclerotomy in the eyes.

Keywords: Human amniotic membrane, pars plana vitrectomy, sclerotomy, silicone oil tamponade


How to Cite

Khaqan, Hussain Ahmad, Laraib Hassan, Hafiz Ateeq ur Rehman, Aamna Jabran, Nabeel Akram, and Ahmad Fauzan. 2024. “Human Amniotic Membrane Graft Plug for Sclerotomy Closure of 23-Gauge Pars Plana Vitrectomy in Eyes With Silicone Oil Tamponade”. Journal of Advances in Medical and Pharmaceutical Sciences 26 (5):42-48. https://doi.org/10.9734/jamps/2024/v26i5685.