Evaluating the Therapeutic Efficacy of L-Lysine Aescinat Supplementation on Neurological Outcomes in Patients with Spinal Fractures and Traumatic Spine Injuries: A Prospective Cohort Study from Tbilisi, Georgia
Koka Gogichashvili *
Caucasus Medical Centre, Tbilisi, Georgia.
Zviad Malazonia
Caucasus Medical Centre, Tbilisi, Georgia.
Tornike Kldiashvili
Caucasus Medical Centre, Tbilisi, Georgia.
Ciara Francesca Maxwell
New Vision University, Tbilisi, Georgia.
*Author to whom correspondence should be addressed.
Abstract
This prospective study aimed to comprehensively investigate the impact of L-Lysine aescinat supplementation on the neurological outcomes of patients recovering from spinal fractures and traumatic spine injuries. A total of 32 patients were recruited and categorised into two groups: Group A (n=16), receiving L-Lysine aescinat supplementation, and Group B (N=16), serving as the control group without L-Lysine aescinat administration. The primary objective was to assess changes in the Karnofsky performance scale, a functional and well-being neurological assessment tool especially for those undergoing operations or with chronic illness, over a follow up period of one month in order to determine if L-Lysine aescinat had an immediate effect on recovery in the post-operative period. Urinary dysfunction was noted, alongside the location of the fracture, type of surgery and if there were any significant comorbidities.
Keywords: Therapeutic efficacy, L-Lysine supplementation, neurological outcomes, spinal fractures, traumatic spine injuries