Role of Platelet Rich Plasma in the Treatment of Foot Ulcers: A Review
Shivani Kshirsagar *
Department of General Surgery, JNMC, Sawangi (Meghe), India.
Chandrashekhar Mahakalkar
Department of General Surgery, JNMC, Sawangi (Meghe), India.
Anshu Agarwal
Department of Medicine, JNMC, Sawangi (Meghe), India.
Meghali Kaple
Department of Biochemistry, JNMC, Sawangi (Meghe), India.
Siddharth Mendiratta
Department of General Surgery, JNMC, Sawangi (Meghe), India.
*Author to whom correspondence should be addressed.
Abstract
An ulcer is a breach in the continuity of epithelium of mucous membrane and skin when an inflamed necrotic tissue sloughs out. Ulcers are caused by various medical conditions. The key to treatment is daily conventional dressing till the formation of healthy granulation tissue, infection control by antibiotics and surgical intervention such as debridement, and if the need arises, amputations. Platelet Rich Plasma (PRP) uses autologous plasma containing growth factors that helps in wound healing. PRP is being used extensively and is under research for wound treatment.
Keywords: Foot ulcers, PRP, dressing