Management of Advanced Stages of Chronic Kidney Disease Patients with the Administration of Renadyl Capsule: A Single Center Pilot Study in Bangladesh
Tanjina Rahman
Department of Nutrition and Food Science, Wayne State University, Detroit, MI, USA.
Sampurna Guhathakurta
Department of Nutrition and Food Science, Wayne State University, Detroit, MI, USA.
Akibul Islam Chowdhury
Department of Food Technology and Nutrition Science, Noakhali Science and Technology University, Noakhali- 3814, Bangladesh.
Fahmida Karim Munni
Kidney Foundation Hospital and Research Institute, Bangladesh.
Harun Ur- Rashid
Kidney Foundation Hospital and Research Institute, Bangladesh.
Shakib Arefin
Kidney Foundation Hospital and Research Institute, Bangladesh.
M. Akhtaruzzaman
Institute of Nutrition and Food Science, University of Dhaka, Bangladesh.
Mohammad Asadul Habib *
Department of Food Technology and Nutrition Science, Noakhali Science and Technology University, Noakhali- 3814, Bangladesh.
*Author to whom correspondence should be addressed.
Abstract
Background: Chronic kidney diseases become a public health concern as the rate of this diseases is increasing. Thus, the aim of the study was to evaluate the changes in key biomarkers in Bangladeshi CKD stages IV and V patients by using Renadyl capsule.
Study Design: Open label randomized placebo controlled clinical trial.
Methods: Data were collected from patients with CKD stage IV and V in 2017, in an out-patient setting in Kidney Foundation Hospital and Research Institute, Bangladesh. Patient’s information, medical history and clinical data were also collected. Health condition of the patients was collected by using SF-36 QOL questionnaire. Data were analyzed using SPSS software version 23.0.
Results: Administration of Renadyl capsule improved the clinical and biochemical data of the patients. Renadyl administration improved the filtration rate, kidney size, creatinine level, heart rate and liver function. Patient’s physical and mental health was also improved.
Conclusion: Renadyl administration appeared to be safe among chronic kidney patients with improved kidney function. However, more clinical trials are suggested to determine the efficacy and effects of Renadyl.
Keywords: Chronic kidney diseases, Renadyl, kidney patients, Bangladesh.