Does Allergic Rhinitis have any Effect on Choroidal Thickness?

Main Article Content

Raşit Kiliç
Harun Soyaliç

Abstract

Aim: The aim of this study is to compare the choroidal thickness between patients with allergic rhinitis (AR) and healthy controls.

Study Design: Prospective case-control study.

Methodology: This cross sectional case control study consisted of 52 patients with AR and 52 healthy subjects. The choroidal thicknesses were measured horizontally with the digital calipers provided by the Heidelberg Spectralis software. The points of measurements were at the subfovea, 1500 µm nasal and 1500 µm temporal to the center of the fovea. The right eye was assessed in all participants.

Results: There was no statistically significant difference between the groups for age and gender distribution, intraocular pressure and spherical equivalent. Mean subfoveal choroidal thickness, nasal choroidal thickness and temporal choroidal thickness were 382.1±121.7, 328.6±111.8 and 368.1±98.2 in AR patients and 378.5±87, 309±77 and 354.2±94.2 in healthy subjects respectively. These differences were not found statistically significant (P˃0.05).

Conclusion: Choroidal thickness in AR patients was found to be thicker, but not statistically significant.

Keywords:
Allergic rhinitis, choroidal thickness, inflammation, optical coherence tomography.

Article Details

How to Cite
Kiliç, R., & Soyaliç, H. (2020). Does Allergic Rhinitis have any Effect on Choroidal Thickness?. Journal of Advances in Medical and Pharmaceutical Sciences, 22(12), 9-13. https://doi.org/10.9734/jamps/2020/v22i1230206
Section
Original Research Article

References

Kakli HA, Riley TD. Allergic rhinitis. Prim Care. 2016;43(3):465-75.

Eifan AO, Durham SR. Pathogenesis of rhinitis. Clin Exp Allergy. 2016;46(9):1139-51.

Mrejen S, Spaide RF. Optical coherence tomography: İmaging of the choroid and beyond. Surv Ophthalmol. 2013;58(5):387-29.

Chung SE, Kang SW, Lee JH, Kim YT. Choroidal thickness in polypoidal choroidal vasculopathy and exudative age-related macular degeneration. Ophthalmology. 2011;118(5):840–5.

Brandl C, Helbig H, Gamulescu MA. Choroidal thickness measurements during central serous chorioretinopathy treatment. Int Ophthalmol. 2014;34(1):7-13.

Ishikawa S, Taguchi M, Muraoka T, Sakurai Y, Kanda T, Takeuchi M. Changes in subfoveal choroidal thickness associated with uveitis activity in patients with Behcet’sdisease. Br J Ophthalmol. 2014;98(11):1508-13.

Güngör SG, Akkoyun I, Reyhan NH, Yeşilırmak N, Yılmaz G. Choroidal thickness in ocular sarcoidosis during quiescent phase using enhanced depth imaging optical coherence tomography. OculImmunol Inflamm. 2014;22(4):287-93.

Hirooka K, Saito W, Namba K, Takemoto Y, Mizuuchi K, Uno T, Tagawa Y, et al. Relationship between choroidal bloodflow velocity and choroidal thickness during systemic corticosteroid therapy for Vogt-Koyanagi-Harada disease. Graefes Arch Clin Exp Ophthalmol. 2015;253(4):609-17.

Bayrak Degirmenci P, Aksun S, Altin Z, Bilgir F, Arslan IB, Colak H, Ural B et al. Allergic rhinitis and its relationship with IL-10, IL-17, TGF-β, IFN-γ, IL 22, and IL-35. Dis Markers. 2018;2018:9131432.

Ciprandi G, De Amici M, Tosca M, Marseglia G. Serum transforming growth factor-beta levels depend on allergen exposure in allergic rhinitis. Int Arch Allergy Immunol. 2010;152(1):66-70.

Spaide RF, Koizumi H, Pozzoni MC. Enhanced depth imaging spectral-domain optical coherence tomography. Am J Ophthalmol. 2008;146(4):496-500.

Fujiwara T, Imamura Y, Margolis R, Slakter JS, Spaide RF. Enhanced depth imaging optical coherence tomography of the choroid in highly myopiceyes. Am J Ophthalmol. 2010;148(3):445–50.

Gallego-Pinazo R, Dolz-Marco R, Gómez-Ulla F, Mrejen S, Freund KB. Pachychoroid diseases of the macula. Med Hypothesis Discov Innov Ophthalmol. 2014;3(4):111-5.

Akay F, Gundogan FC, Yolcu U, Toyran S, Uzun S. Choroidal thickness in systemic arterial hypertension. Eur J Ophthalmol. 2016;26(2):152-7.

Unsal E, Eltutar K, Zirtiloğlu S, Dinçer N, Ozdoğan Erkul S, Güngel H. Choroidal thickness in patients with diabetic retinopathy. Clin Ophthalmol. 2014;8:637-42.

Kılıç R, Kurt A, Ergül B. The evaluation of choroidal thickness in patients with chronic hepatitis B virus infection. Ret-Vit. 2018; 27:37-41.

Kurt A, Kılıç R. The effect of Ramadan Fasting on choroidal and retinal thickness measurements: A pilot study. Ret Vit. 2018;27:146-150.

Kola M, Kalkisim A, Karkucak M, Turk A, Capkin E, Can I, et al. Evaluation of choroidal thickness in ankylosing spondylitis using optical coherence tomography. OculImmunol Inflamm. 2014; 22(6):434-8.

Onal IK, Yuksel E, Bayrakceken K, Demir MM, Karaca EE, Ibis M, et al. Measurement and clinical implications of choroidal thickness in patients with inflammatory bowel disease. Arq Bras Oftalmol. 2015; 78(5):278-2.

Kılıç R, Kurt A, Acer E, Öktem Ç, Kocamış Ö. Choroidal thickness in psoriasis. Int Ophthalmol. 2017;37(1):173-7.

Türkcü FM, Şahin A, Yüksel H, Akkurt M, Uçmak D, Çınar Y, et al. Evaluation of choroidal thickness in psoriasis using optical coherence tomography. Int Ophthalmol. 2016;36(6):851-4.

Kurt A, Kılıç R, Ergül B, Öktem, Ç. Evaluation of choroidal thickness in patients with ulcerative colitis. Sudanese J Ophthalmol. 2016;8(2):51-5.

Kurt A, Kurt EE, Kılıç R, Öktem C, Tuncay F,Erdem HR. Is choroidal thickness related with disease activity and joint damage in patient with rheumatoid arthritis. Bratisl Lek Listy. 2017;118(1):23-7.

McGeer PL, Sibley J. Sparing of age-related macular degeneration in rheumatoid arthritis. Neurobiol Aging. 2005;26(8):1199-203.

Yenigun A, Elbay A, Dogan R, Ozturan O, Ozdemir MH. The effect of allergic rhinitis with positive skin prick test on choroidal thickness. Eur Arch Otorhinolaryngol. 2017;274(6):2477-81.