Eruptive Seborrhoeic Keratoses Induced by Oral Esomeprazole: A Coincidental Finding or Linked Pathogenesis?
Nilay Duman *
Department of Dermatology, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey
Çiğdem Özdemir
Department of Pathology, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey
Serap Polat
Department of Dermatology, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey
*Author to whom correspondence should be addressed.
Abstract
Aim: Eruptive seborrhoeic keratoses are characterized by rapid onset of multiple seborrhoeic keratoses. They can be associated with internal malignancies, inflammatory dermatoses and drug reactions. Our aim was to present a case with eruptive seborrhoeic keratoses appeared during treatment with oral esomaprazole and to discuss possible etiopathogenesis.
Presentation of Case: Herein we report a 24-year-old female patient with eruptive seborrhoeic keratoses appeared during 1-year treatment with oral esomeprazole.
Discussion and Conclusion: Although, the association between esomeprazole treatment and eruptive seborrhoeic keratoses may be a coincidence, previously reported growth factor changes in both conditions may be pointing out a linked pathogenesis.
Keywords: Eruptive seborrhoeic keratoses, esomeprazole, leser-trélat sign, epidermal growth factor