Extended Spectrum β-Lactamases among Enterobacteriaceae Isolated from Clinical Specimens of a Tertiary Hospital in 2014
Maefael Dianne M. Garcia *
Medical Technology Program, College of Arts, Sciences and Education, Colegio San Agustin, Bacolod, Philippines
Ina Loiuse P. Norre
Medical Technology Program, College of Arts, Sciences and Education, Colegio San Agustin, Bacolod, Philippines
Amel Myrnel N. Gicana
Medical Technology Program, College of Arts, Sciences and Education, Colegio San Agustin, Bacolod, Philippines
Rogelio Rr Tariman
Medical Technology Program, College of Arts, Sciences and Education, Colegio San Agustin, Bacolod, Philippines
Kristine B. Rigby
Medical Technology Program, College of Arts, Sciences and Education, Colegio San Agustin, Bacolod, Philippines
*Author to whom correspondence should be addressed.
Abstract
Extended spectrum beta-lactamase producing Enterobacteriaceae have become widespread among hospitals and even in the community. Such phenomenon poses a therapeutic dilemma against certain antimicrobial drugs that limit therapeutic options. This study was conducted to evaluate the prevalence of ESBL producing Enterobacteriaceae in a tertiary hospital in Bacolod City and their antibiotic resistance profile for the year 2014. Out of 662 isolates, 125 (18.89%) were found to be ESBL producing and were frequently seen in Escherichia coli (4.96%), Klebsiella pneumoniae (4.08%) and Enterobacter aerogenes (3.36%). Urine was found to be the most common specimen to contain this type of bacteria (7.70%), followed by wounds and abscess (5.14%), and sputum (3.63%). These isolates were also found to be least resistant to amikacin with 10.5% followed by imipenem and meropenem with 17.1% and 15.4% respectively. Furthermore, there was no significant difference with regard to sex, but with significant difference in terms of age.
Keywords: Extended spectrum β-lactamases, Enterobacteriaceae, tertiary hospital, Bacolod city